Is Upstream Bio, Inc. overvalued?

Upstream Bio, Inc. (UPB) — key valuation metrics and fundamentals.

No verdict

Price

$2.78

Fair value

—

Current P/E

—

Normal P/E

—

Market cap

$152.4M

Dividend yield

0.0%

Return on equity

-57.1%

Sector

Healthcare

Fair value compares UPB's current P/E to its own historical "normal" P/E (FAST Graphs-style). Updated 12 Nov 2026.

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